Drenwas created by Elsa and Clive, two scientists who mixed human with multiple animal DNA. Dren is a monster in the 2009 live action film,Splice, and the main antagonistby the endof the film. Eventually, she transitions from female to male. She matures fast as she was about six years old after twenty something days. Splice is a 2009 science fiction horror film directed by Vincenzo Natali and starring Adrien Brody, Sarah Polley, and Delphine Chanéac.The story concerns experiments in genetic engineering being done by a young scientific couple, who attempt to introduce human DNA into their work of splicing animal genes. Enjoy the videos and music you love, upload original content, and share it all with friends, family, and the world on YouTube. In her infant form, Dren is a two-legged creature with pale skin, minimal facial features, a theropod-like stance, and digitigrade legs. She (sometimes he) is portrayed by Delphine Chanéac. As she grows, she learns to stand more erect and gains a more human-like face, as well as a long prehensile tail and feet resembling high heeled shoes. Guillermo del Toro, Don Murphy, and Joel Silver are the executive producers of this film.

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